DPCstruct | MC19438

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)69 ± 3 aa
Standard deviation of domain lengths2.67
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score82.90
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.94
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)42.81
Pfam Score100.00
Assigned Pfam label(s) CL0465

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A443SFT2 1-72 MKAKIEDIHRAVTFGKLRNVQQLIDRKKLAFCRDQMGATPLHKAVIYGQTEIIHYLLDKFPSVIHSRDHQCT
A0A2G5S960 97-169 DRLPEYMEKIDGIHRAIKEGNLDEVKELMKTKKLAIARDRYGCTPLHSAVVHEHTDIVRYIAGHYNSVLNAPD
A0A6V7VWG9 72-137 None
A0A1I7W721 307-376 None
A0A5B7I9Z2 6-75 None
T1L684 47-115 None
A0A5S6Q313 63-137 None
A0A0D6LQ70 81-150 None
A0A1I7T976 80-147 None
A0A0M3JLM4 49-114 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.