DPCstruct | MC19433

Metacluster Properties and Pfam Annotations

Number of structural domains80
Mean domain length (aa)98 ± 18 aa
Standard deviation of domain lengths17.92
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score82.04
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)33.13
Pfam Score97.56
Assigned Pfam label(s) CL0112- CL0123- PF01990

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V2U836 2-73 THIAAIGERLRVVGLATAGVVTFPAEDPEAVRAAWRGLPPEVGLVIVTPAAAAALGPGPLDAEDPLTAVMPP
A0A443S8Z7 233-332 LLAVIGDEDTCVGFLLGGIGEINRTKTPQLNFMVVDKNTVTSEIEETFKGFLKRDDIDIILINQNVAELIRHAIDSHVEAVPAVLEI…
A0A6A4NM03 1-86 None
A0A846NYI9 2-88 None
A0A0R3T8N6 10-110 None
A0A7R9B8P9 43-136 None
A0A7J6LZ72 9-124 None
A0A2H4SLD5 9-120 None
B0EQN5 13-93 None
A0A7R9UB00 54-163 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.