DPCstruct | MC19428

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)87 ± 3 aa
Standard deviation of domain lengths3.31
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score83.47
Mean fraction of residues predicted as intrinsically disordered0.54
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)51.83
Pfam Score100.00
Assigned Pfam label(s) CL0584

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A443RZ33 1-91 MKDKLSAAKTEFRDLLKETKIITFKSKKMIEESEQHLQDIVAILQNDKRYLILDCIEDERRHLLMAYIDELDRKGPPPPPTASEPTR…
A0A336N1F6 135-218 DKTLLAKASFRELLSETKLITHKSFEMVKENPNHLKEIEEILKNDKRYLDLEHIHHERSSMLNNYLEDLMKRGPPPPPTATNRN
A0A069DXB0 776-865 None
A0A4C1UMF8 355-444 None
A0A2W1B7W1 132-220 None
A0A1B0C2Z6 1-89 None
A0A034VWB4 56-142 None
A0A1A9XUP1 1-85 None
A0A3Q0IUW2 260-348 None
A0A6J1P4F4 122-209 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.