DPCstruct | MC19413

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)105 ± 18 aa
Standard deviation of domain lengths18.05
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score78.74
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)23.99
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q38CF3 305-394 LITTHHRCHFRGDSWVGLLREKPQAMQAALLKDISLELRAPYGFITIATMESVSELVVFDVIIRHPVSLSEDDVELRLIGCSFDEMS…
A0A1X0P7P7 204-297 EESSEIMKTKHTIRFRGLKWKRILKRKRSVLEEALKKDISAATGFNEKEIFCLDIEFKVALIVTFVLQHKSDTESKEIHTLLHRYDY…
A0A2V2X6I9 32-150 None
W6KWG0 40-128 None
A0A2V2XEQ2 116-215 None
A0A7J6XTL3 385-499 None
A0A836HIB9 290-394 None
A0A836HV69 1094-1212 None
A0A2V2VF26 311-411 None
A0A2V2VT39 152-261 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.