DPCstruct | MC19408

Metacluster Properties and Pfam Annotations

Number of structural domains113
Mean domain length (aa)150 ± 27 aa
Standard deviation of domain lengths26.72
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.31
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)18.30
Pfam Score85.29
Assigned Pfam label(s) CL0063- CL0722- CL0697

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T7YGN1 3-121 IGTVANKLFQGLPKKVVVKYYESFAETHKGHGTDFAIIAGILGLAADDSKVPDAIKIAESKGIDITFIEQLGNSPAGHPNTADVYAE…
A0A854ZT33 10-135 IGPITIGTPSANGVEATKIGHIVRQLFLKTPEKIEISLYGAFKKTDCTFGSDVALVGGILGLEMDDSLFSKALTIATERGITVNCIE…
A0A7X6X771 14-139 None
A0A6C8GK61 2-120 None
A0A2X2E0T1 4-169 None
A0A6G9WN51 3-139 None
A0A7C6YL27 4-162 None
U2WB03 67-240 None
A0A0C3C948 129-255 None
C2FS65 4-190 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.