DPCstruct | MC19388

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)128 ± 10 aa
Standard deviation of domain lengths9.96
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score80.62
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)19.40
Pfam Score100.00
Assigned Pfam label(s) PF20346

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B0SZH9 8-136 KLVAAKPAPADAKGRNREKLVRYLAEQKALVAAHLAGEPFNATRVVTRKDEAGNRTRVEAPRHVRRGWFTDASGGLFFTLRYGAKPL…
A0A2A4R131 29-176 MSILSKLTLTATSPREPITPLARKRIKLLNRIEQQISAAEAELRDEQFMEEIKRWVRNEETGDKTLISTERPVRKWWWKNQHGAWMI…
A0A2D5PV40 17-126 None
A0A6P1GEP1 1-121 None
A0A7W5NCG9 1-113 None
A0A2M8U7L0 1-143 None
A0A2D7C1P5 4-134 None
A0A7W6CMZ4 2-124 None
A0A197BUJ9 37-158 None
A0A5J5I3K2 1-134 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.