DPCstruct | MC19359

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)484 ± 112 aa
Standard deviation of domain lengths112.31
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score78.91
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)29.11
Pfam Score77.47
Assigned Pfam label(s) CL0257- PF07965- CL0128- PF08725- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0K0FWY8 52-476 KNQMRLTQNTHRFSKEVQEAQISGNLDAPEGGFDAVMQTLTCNKSIGWRERARKMIVFSTDAGFHYAGDGRLAGVVTPNDGQCHLDD…
A0A6J2WG71 146-661 AKLRQAVLTAVQEVNAKAVSTGSGLFGEEQKQGCKESVCGKVLHLTHSSHGPPGAPHSEGTSSHGGLQALLQTALCRDEISKEQDPW…
A0A0C2IMW7 48-364 None
A0A0C2J525 94-556 None
A0A0C2JQA2 142-549 None
A0A212CIL6 135-695 None
A0A498NY70 380-864 None
F1RA51 134-730 None
A0A1X7SEP6 2-346 None
A0A7J5YV27 171-517 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.