DPCstruct | MC19344

Metacluster Properties and Pfam Annotations

Number of structural domains53
Mean domain length (aa)128 ± 21 aa
Standard deviation of domain lengths21.01
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score67.96
Mean fraction of residues predicted as intrinsically disordered0.88
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)45.73
Pfam Score100.00
Assigned Pfam label(s) PF10159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4T0TSC7 1-112 MEGEPIRGGTRGGAGNFSWNAVKEDKHREYYLGHSVKAAAGRWQKNKDIHWYNRDQDSGDEEEVKRKKKAEIQKIKEAEEDALSLAL…
A0A1X0R7G5 1-130 MFHPTRGGTRGGRDQFSWEDVKQDKHRENYLGHSLMAPVGRWQKGKDLQWYTKKATDDAKAKADKSELQKIKEAEAEAMAIALGVRK…
A0A0D3H363 1-98 None
A0A4U0VU52 1-148 None
S3BM23 1-129 None
A0A4S9U7B5 60-185 None
A0A2T3AJQ1 5-114 None
A0A1E3J016 1-111 None
A0A674H621 403-535 None
A0A4D8ZKK9 1-159 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.