DPCstruct | MC19330

Metacluster Properties and Pfam Annotations

Number of structural domains845
Mean domain length (aa)313 ± 56 aa
Standard deviation of domain lengths56.32
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score80.67
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.05
Pfam Score98.64
Assigned Pfam label(s) PF00786- PF00566- PF11830- CL0063- PF19430

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2R8QAX8 49-329 LPHLKDAIFKGGLCHAVRKEAWKFLLGYFPWSSTHEERKLLQKRKTDEYFRMKLQWKSVSEEQERRNSRLRDYRSLIEKDVNRTDRN…
A0A2I1CLP2 45-388 MEIYSSRISRINKFKRLLQTSTVSLSELRNLAWSGIPAEVRAMTWQILLGYLPTNSERRVSTLERKRKEYLDGVRQAFERSTSPASG…
A0A6S7NB26 474-819 None
A0A2B4SQI5 85-422 None
A0A7S4RNW1 366-676 None
A0A397FJL7 7-220 None
A0A7S2J6U9 47-330 None
A0A182F673 291-599 None
E7F6L2 33-371 None
A0A672URZ6 408-714 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.