DPCstruct | MC19315

Metacluster Properties and Pfam Annotations

Number of structural domains51
Mean domain length (aa)73 ± 7 aa
Standard deviation of domain lengths6.74
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score89.88
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)53.60
Pfam Score100.00
Assigned Pfam label(s) CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A818VQW3 225-299 None
A0A6J0J9H0 75-149 None
A0A349RFM2 120-194 None
A0A3B3QZD7 325-399 None
A0A182G2W6 170-244 None
A0A183KM11 151-229 None
H3C716 2-79 None
T1JNH6 146-223 None
V5YQL4 864-938 None
A0A6P4FMM5 43-120 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.