DPCstruct | MC19288

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)249 ± 40 aa
Standard deviation of domain lengths39.55
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score81.47
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)35.72
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A3HSC6 3-241 TVDGKSCVKPTPSSPEGLAAFLDVTSTQHPCQRLRTKLPELGFFMSPKVLHRVESRRSSPKTAPPVEIVVECWLKCRGERPDLMKIF…
A0A225UDV7 58-309 VPSDAEIKCTTVGIQKCCKFMDPDHPWRKAMDLWPEHACLFDTTDFQLDSHISQRADYPERLCGVWQRLRGYGSKKQAVMSFAIYER…
A0A6A3KAS0 193-443 None
A0A225W8S3 106-367 None
A0A225WIH0 410-651 None
W2P115 16-217 None
A0A6A3YVQ6 116-441 None
G4ZDJ0 568-811 None
A0A6A3RH29 734-1061 None
W2M5E2 5-225 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.