DPCstruct | MC19287

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)206 ± 34 aa
Standard deviation of domain lengths34.22
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score72.13
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)25.57
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A3MSZ4 188-369 LRAFCGRVGIKAYKNKSKAELLELIAQKKKDDKLYKPIFDAKMAERREPSRKQIQCPFRLLNIMFSDHFADRFVSLADQRSRADLDA…
A0A6A3HR69 18-245 GAKALRSECRRLKATPTAHNKASYLAALRASLVVAGTIEASGVVQDPFLGADVVRKTVACVFRLLNVLFSDVFCAGVATLGDVATRQ…
G4ZWN6 2-284 None
W2HKX2 18-230 None
A0A225WXA5 5-241 None
A0A6A3YRX0 1-155 None
A0A6A3ZK55 33-292 None
D0P141 8-250 None
A0A6A3IND6 523-754 None
D0MRL6 7-211 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.