DPCstruct | MC19263

Metacluster Properties and Pfam Annotations

Number of structural domains627
Mean domain length (aa)182 ± 45 aa
Standard deviation of domain lengths44.65
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score82.96
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)14.30
Pfam Score97.10
Assigned Pfam label(s) CL0163- CL0236- CL0021

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A846D3U9 2-135 LITTIKYGLEVHFKDDPNVFVAGDLLWYPIQGQPKINQAPDVMVVIGRPKGHRRSYKTWVEDNLNPQVTFEIASLTNTIKELEDDKL…
A0A2B7XXA6 4-193 LSDMDLRQESRKRRINYHRSPHILIVKIPCVLTEVAISSFGMLATLFLCEMGLFWDLLATGAAHVEGSERTKCPYCSYRPFQLPRGR…
A0A3N4IRY9 27-259 None
Q2MG43 7-145 None
A0A1L9WJK0 3-156 None
A0A1L9TI10 55-183 None
A0A7S2RDA1 10-146 None
F4PLW0 43-216 None
A0A518I1K5 62-240 None
A0A3N4IX30 1-317 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.