DPCstruct | MC19232

Metacluster Properties and Pfam Annotations

Number of structural domains66
Mean domain length (aa)149 ± 29 aa
Standard deviation of domain lengths28.65
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score75.99
Mean fraction of residues predicted as intrinsically disordered0.44
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)35.13
Pfam Score97.78
Assigned Pfam label(s) PF10149- CL0293- PF05832

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183BWS6 126-245 WVLLVCTAFLTLQWQWMLSLHSADLWAVKNVTGRLMVGLRWWSLVDADGKNHWKFEISQDSEKYDAFERQIFWAALVAAPFFWALLV…
A0A061AJA2 12-161 LDTNQDNQAPSSHTYLDCFSPITFILLLAADFWNVKNISGRLLVGLRWWNETDDNGESIWVFETANPDRVINPIDSKVFWIMLYSTP…
A0A7J6U7T9 39-225 None
A0A7J8J3E3 1-93 None
A0A0D8XVW3 223-389 None
A0A0V0R0T3 47-174 None
A0A2K5MX81 73-178 None
A0A0D2N4X7 7-104 None
A0A7T8KJM0 16-129 None
D3B7H3 223-381 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.