DPCstruct | MC19186

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)151 ± 16 aa
Standard deviation of domain lengths16.39
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score85.03
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)37.48
Pfam Score100.00
Assigned Pfam label(s) PF05936

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q5GYC7 647-805 MARIVECRADRRVILDDAFIPTAIRIEGAARLSMLLAELLGLLHQRGQALADRVAGSDRRGVAEIADVLMLQVINRYQPLVAHWASA…
A0A2U2H9V4 145-290 LRVRRLANGGFELDPAFVPPSLTVHGAPALLLHLRCLIDTLQANVDALHAHQHTPGRHAGQIRCGGMSTFRLLHTASSALASLSYYF…
A0A3M2WBC3 280-430 None
A0A356RDF8 230-369 None
A0A447WC42 686-857 None
A0A6N6X5D9 1-139 None
W1DPM5 1-124 None
A0A443XEC3 168-343 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.