DPCstruct | MC19183

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)409 ± 78 aa
Standard deviation of domain lengths77.71
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score71.65
Mean fraction of residues predicted as intrinsically disordered0.62
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)43.35
Pfam Score91.11
Assigned Pfam label(s) CL0344- CL0105- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1J4YQX0 4-272 TNGYLMGGPMMGIRLPSEQVGIIKATNCIIAMSDVLFPPAPPALPCIRCTRCAEACPAELQPQELYWFAKAKNFDKARKYNLFDCIE…
A0A7H4MXZ0 2-320 VIMGGPLMGFTLPWLDVPVVKITNCLLAPSASEMGEPEEEKGCIRCSACADACPADLLPQQLYWFSKGQQHDKATSHNLADCIECGA…
A0A080M5A2 36-290 None
A0A0U5GLE4 1-511 None
A0A379WAD6 116-573 None
A0A498CMN1 136-555 None
A0A379GI14 136-657 None
A0A2T7B5M4 273-770 None
A0A090SDZ1 47-454 None
A0A377A0V6 2-349 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.