DPCstruct | MC19174

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)129 ± 15 aa
Standard deviation of domain lengths15.39
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score83.50
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)18.89
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A4YSB2 9-137 KTSLIIALIRMARVDGRVNHYEQMNISMLTNTLGVNHAEVALLAKDIDNVPVVVPVTREDKVKYFWRILIMMKMDLQAHEKELKLAQ…
A0A1Q2MGH3 250-407 SRLFLHNILAVARADSYLDGSEVKLIKSFCKKAGIGQNEYDKILRESINNPGNVILNGSPDEQWGTLLTLIKVAMADGQMSKDEIDI…
A0A3N5G1R6 2-140 None
A0A848J1H9 2-145 None
A0A848IYK1 4-132 None
A0A6C0GD80 3-145 None
A0A356KZT1 356-462 None
A0A356KTF2 1-118 None
A1ZFK0 3-117 None
A0A1X7L8P3 15-127 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.