DPCstruct | MC19158

Metacluster Properties and Pfam Annotations

Number of structural domains68
Mean domain length (aa)218 ± 43 aa
Standard deviation of domain lengths42.99
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score75.58
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.54
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A420TZX6 246-412 VDPHPKEDEEEDEEEEIKCKVCGNPNHTVSTCFSHTGKGQTFGCPLCDAADHTGSDCAEIAKLSLTEQVKLLITNRGNMPAFHEGPK…
A0A0J0CD86 19-219 MSAIIPDKFEAIERDHTQKVVMNNDFGDKGGKPVGLFGRNIQAPSEKKHVVKGWCKLCGSKSHTLTDCVMRGYKGHVTGCPICNDQK…
A0A366S8F3 188-427 None
A0A5C6T8Q9 1040-1238 None
A0A2K0W6P6 7-172 None
A0A365MYE9 26-231 None
A0A365MKA4 141-314 None
A0A1B7YQG1 1-216 None
R8BUP9 144-356 None
I1RRA8 17-273 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.