DPCstruct | MC19143

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)230 ± 32 aa
Standard deviation of domain lengths32.37
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score85.40
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)26.33
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W0QB25 9-139 EVTPTRLRDVFALALDNAVEGCVHEAFAAVLCRFQAVTCRDLALAADLDVIAEDEARHGELAWAIARWLEPQLTAAQRAVVERARAV…
A0A2W5VT13 100-302 DMPGRPPTNGRLPDEAEPWARMAWFEAQSAHEFEHLATQLEALGAPSHFVSRARAAAVEERGHARIAERRAGRVVTVDDTPFRSRTV…
A0A1I2H5A8 242-492 None
A0A7S3PNL1 42-277 None
A0A2S9YIQ5 3-225 None
A0A3S5GY27 3-187 None
A0A3A8GJQ9 81-316 None
A0A849ZM85 43-300 None
A0A3A8P5C1 47-262 None
A0A1M3NEJ9 50-284 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.