DPCstruct | MC19106

Metacluster Properties and Pfam Annotations

Number of structural domains65
Mean domain length (aa)269 ± 30 aa
Standard deviation of domain lengths29.75
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score76.31
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)14.99
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0F8UEX1 4-241 ICSFWDAGCVDPLAQTAIAFGFPPLFLENMNLFYAFDADPRGKGQEPMTKVSFWIGYEAYINNSVIDLNRTSEIGMRVGNLTGSPSG…
A0A136ISU6 26-299 SSTAASLSPVQLVARNNTDLGDFLSNPNPDVSGRVNMPGFRLDTTYPGAGGTKPWSLELNITRWAESSMFPGNNATRISAQIIPPSP…
A0A4Z0ZA95 24-318 None
Q2GRS6 22-271 None
A0A507BHH2 43-310 None
N4VKZ4 119-436 None
A0A364N7T8 1-281 None
A0A1B7YQY4 4-249 None
A0A2T2P0C7 17-363 None
A0A0F4YJ80 114-407 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.