DPCstruct | MC19069

Metacluster Properties and Pfam Annotations

Number of structural domains825
Mean domain length (aa)117 ± 21 aa
Standard deviation of domain lengths20.59
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score79.83
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)21.78
Pfam Score96.28
Assigned Pfam label(s) CL0550- CL0168- CL0056- CL0692- PF07692

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A834DJ09 3-93 GNLGCYKDHGNPPPLTGASKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWTYGEAASTECNSVCFGDHAQPCGGDGRI…
A0A094A294 16-135 ANSLAIEKPAIIRQRDGWSLLGCFTDNVSGRALPNGVSVPGGSGSITNEACQTACLAAGYKVAGTEYGGECWCGNAVTNGGALVSDG…
A0A813NX49 551-638 None
A0A1A6A6P8 138-262 None
A0A813U397 20-130 None
A0A6S7HBG0 663-768 None
A0A6S7IGX2 267-369 None
A0A2K6AUQ2 128-233 None
Q2GQ20 10-125 None
A0A813R1G5 645-774 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.