DPCstruct | MC19052

Metacluster Properties and Pfam Annotations

Number of structural domains69
Mean domain length (aa)250 ± 39 aa
Standard deviation of domain lengths39.35
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score81.95
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)27.72
Pfam Score79.55
Assigned Pfam label(s) CL0023- PF12359- PF12340

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A022XFS6 37-281 IKIHDWMQTVCRDVLDECDYTLAPRTQLIYPSGTQCTVDGHPHRWQTAEKLLELVSGHIWGLWQRYPGSIEVIQRPKGGFPIVYFLR…
A0A5N5CTH5 9-269 ERLQTQPELGWQLVRAEQWLATTCRDVLDESDEILDPRFQLVYSIGNQRLMDGQPDRWVITQRLLSLFADQARVLQAQGNQGVEVDS…
A0A820TGL9 6-200 None
A0A820T5Z1 41-256 None
A0A0D2G9G7 4-228 None
A0A822DX26 354-654 None
H0EN30 364-598 None
A0A2K0UV93 858-1147 None
A0A834S6Q8 5-243 None
A0A6A4DH99 528-776 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.