DPCstruct | MC19026

Metacluster Properties and Pfam Annotations

Number of structural domains146
Mean domain length (aa)134 ± 23 aa
Standard deviation of domain lengths23.02
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.93
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)18.12
Pfam Score98.08
Assigned Pfam label(s) CL0023- CL0200- CL0172- CL0159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E3GXD5 7-133 LEEILAELKVYQEQSEIIKQQIDTIRSTIAELDMLDETLDAIDGKEGAEIFVPIGAGSFALAELKDTKNVIMSVGAGIAIKKSIKDA…
A0A7J3CJP3 22-149 DNEQEFEQAYLEFQIIQQQMLQIQEQVKMFENQEKELVIALNAISQLQKIEGKNKVLVPVVNGIFIEGELKKPENFIINIGGNVAVK…
A0A5S6QHQ8 148-303 None
A0A4T0G9N7 28-180 None
A0A3Q0IJ92 8-101 None
A0A0V0Q7J7 2-109 None
A0A4Y7L7N3 235-362 None
A0A1S3P3X8 1-121 None
A0A446JU32 5-86 None
A0A388KYV9 18-156 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.