DPCstruct | MC19019

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)107 ± 18 aa
Standard deviation of domain lengths18.45
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score75.38
Mean fraction of residues predicted as intrinsically disordered0.66
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)35.22
Pfam Score100.00
Assigned Pfam label(s) PF11842

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A645H8J4 45-126 YTGINPLTGEKVYTPKTQKEKNMQRALLQFKIPKNYNTVKDALIACNREDLIGKGAHCLIGDKEPKNSSNKQNSKNKKSKKR
A0A7X7KIV3 5-107 MYYTGVDPLSGEEVFVPRGDRARRLQRALLQFFLPENYVDVRAALEEADRADLIGDGADCLIPSRPPRVADARKPASRQRQNRDKRP…
A0A645J121 27-116 None
T0D2C1 1-104 None
A0A381I6S5 1-98 None
A0A5S3RRB3 6-92 None
R5GXT8 378-491 None
A0A357XUJ5 301-435 None
A0A0B8PEE5 59-162 None
A0A517Y350 1-133 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.