DPCstruct | MC19017

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)91 ± 4 aa
Standard deviation of domain lengths4.31
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score90.46
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)41.78
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A849QJL9 95-185 LEIGEVSVDHNWKRVAFNDTFIDPVVVANPLSYNGGDPAVLRIRNVDNTGFDIRVQEWDYLDGIHAEETVGYMVMERGAYTLPDGTM…
A0A640VQ94 590-675 GQSGTVTVAQSGSDQWHRVVFDTTISDAVVVMGPISWNGLQAATTRVRNVTDEGFEFQIDEWNYLDGAHTTETIGWLAMSEGSHTL
A0A7C4L082 27-120 None
A0A358N5D4 648-731 None
A0A3B9CU96 633-728 None
A0A7Y3DJL8 257-349 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.