DPCstruct | MC19008

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)61 ± 4 aa
Standard deviation of domain lengths3.87
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score87.70
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.93
Mean intra-cluster sequence similarity (%)52.56
Pfam Score100.00
Assigned Pfam label(s) CL0240

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D7G166 15-83 VCNVKYVDPSYMIRSVAANSYDQIYCMQLAQNAVHGAMAGYTAFSVGMVNDRTVYLPMEELVAHSPRIV
A0A078JHQ2 1-63 MVMNLKYVDPAYMIRTVSTNASNTVYFRLLAQSVVHGAVAGYTSYISSLINRRQTYIPYSVSY
A0A4S4DBM4 236-301 None
A0A2U1MHV7 90-153 None
A0A2J7ZS23 196-256 None
A0A6S7MX10 136-191 None
A0A7S0LKF9 104-161 None
A0A834ZP25 253-314 None
A0A392PH64 1-59 None
K0SZ25 116-179 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.