DPCstruct | MC18999

Metacluster Properties and Pfam Annotations

Number of structural domains33
Mean domain length (aa)180 ± 23 aa
Standard deviation of domain lengths23.34
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score69.70
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)22.00
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A8B6C8A0 53-286 SPLNKKKLLEYKTVIRKITAEDTQRLHRKRLLFKVSIKSHSYSSKDCACSLKMTKEMILIPKHKFEAVLQKQNEDQSKAEVVLNDTP…
A0A2A4IZU0 245-444 QTLQRYLHFTEEDRQPLRLPIYSDTFNVDSNESKIGFKNKDRDTKSSFDVESLLDESVSIKSKENEVNSLYTPTQILSLIPKTYNKK…
E2BZF2 242-441 None
A0A661F5L5 26-235 None
A0A7R9AV81 109-298 None
A0A4Y1ZR84 2-146 None
A0A4Y1ZT55 137-345 None
A0A4Y2TN58 16-188 None
A0A7J5V5Y7 140-307 None
A0A7J5V836 1-162 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.