DPCstruct | MC18985

Metacluster Properties and Pfam Annotations

Number of structural domains865
Mean domain length (aa)287 ± 67 aa
Standard deviation of domain lengths66.70
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score76.48
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)14.44
Pfam Score95.48
Assigned Pfam label(s) PF05300- PF10163- CL0113- PF09781- PF13127

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A366Q7Q3 438-782 None
A0A820JFR8 9-253 None
A0A0C3KWI8 400-826 None
H9IXW0 2-245 None
A0A2C8F3S6 9-214 None
A0A163JRX3 20-317 None
A0A4S4LFB9 111-309 None
A0A3B6DPG4 8-350 None
A0A0E0N8J2 546-875 None
A0A836UXQ1 4-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.