DPCstruct | MC18985

Metacluster Properties and Pfam Annotations

Number of structural domains865
Mean domain length (aa)287 ± 67 aa
Standard deviation of domain lengths66.70
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score76.48
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)14.44
Pfam Score95.48
Assigned Pfam label(s) PF05300- PF10163- CL0113- PF09781- PF13127

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0E0ANF2 20-293 None
A0A1W0ABC4 268-699 None
A0A812IAJ6 6-266 None
A0A812ICE5 283-611 None
A0A812J9T2 673-1026 None
A0A2V5EKK1 7-303 None
A0A7S2W7P3 2-293 None
A0A7V1YJA1 7-262 None
A0A5N5F833 8-252 None
A0A4R3G0I9 6-171 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.