DPCstruct | MC18985

Metacluster Properties and Pfam Annotations

Number of structural domains865
Mean domain length (aa)287 ± 67 aa
Standard deviation of domain lengths66.70
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score76.48
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)14.44
Pfam Score95.48
Assigned Pfam label(s) PF05300- PF10163- CL0113- PF09781- PF13127

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A370HK79 7-282 AWGSGLLGVIIFSGSLPATRVAVGGFSPLFLTSARAVIAALLAAAFLVALRQARPGRGDLRPLAVVALGVVVGFPLLTALALQHITS…
A0A7V1PU88 19-286 SSTWLFIKLGLESMPPFYSAGWRFLVAAFVLFAYGRYLNIPFPRDGHSHRFLFLFGLSIFTISYGLVYWGEQYLSSGLTSVLFSVMP…
A0A0V0QDK1 2-212 None
A0A011Q7A1 26-221 None
A0A0K0EE59 11-270 None
A0A654ET66 4-398 None
A0A6P6GIM8 5-391 None
A0A1D2NA80 10-233 None
A0A1D2NA91 101-420 None
A0A1R3J746 239-619 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.