DPCstruct | MC18982

Metacluster Properties and Pfam Annotations

Number of structural domains115
Mean domain length (aa)285 ± 61 aa
Standard deviation of domain lengths61.21
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score88.24
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)24.54
Pfam Score94.22
Assigned Pfam label(s) PF00710- CL0465- CL0036- PF17763

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I3DI46 223-513 EALIEAVPEIKRLANVKGEQIVKIGSQDMSDDVWLKLAKAINAQCKDTDGFVITHGTDTMEETAYFLDLTAKCEKPIVLVGAMRPAT…
A0A0A2W3Q6 639-928 SGHLQRQLAMMPEFHRPEMPDFTIHEYDPLMDSSDMTPEDWQHIADDIKAHYDEYDGFVILHGTDTMAFTASALSFMLENLSKPVIV…
A0A812IVN5 1-272 None
A0A4U0VJC4 29-376 None
A0A4U0Y0D1 1-238 None
Q6FT22 115-411 None
A0A1Y1V1P7 101-435 None
A0A1R0H910 3-249 None
U6L5J4 137-479 None
A0A395STG8 1-159 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.