DPCstruct | MC18965

Metacluster Properties and Pfam Annotations

Number of structural domains76
Mean domain length (aa)92 ± 11 aa
Standard deviation of domain lengths11.05
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score85.48
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)47.77
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
F2LSC7 1-73 MEHADDIAVDQFAAAMREKMKRSREKGRGGWADKTLCSEKSLSQMLREHVEKGDPVDVANFCMMLHHRGEKIV
A0A6F8UQB6 7-96 FERPWERAERDQIANKAGIKRLKEAMKAKLAAARLKGRGGWQDKDDCSQEHLSKLLREHVEKGDPVDVANFCMMLHARGETILPVAR…
A0A0Q0E9N4 2-77 None
A0A854ET05 94-188 None
A0A7V8F6S6 157-239 None
A0A1S7RUB2 74-171 None
A9ID08 53-147 None
A0A837UXV3 80-169 None
A0A1E7X6Q3 3-92 None
A0A1B4G139 482-567 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.