DPCstruct | MC1896

Metacluster Properties and Pfam Annotations

Number of structural domains374
Mean domain length (aa)292 ± 57 aa
Standard deviation of domain lengths56.95
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score86.27
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)19.74
Pfam Score94.64
Assigned Pfam label(s) CL0023- PF05157- PF17854- CL0306- CL0021

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A429ZEE2 10-302 LLKEGYSQRISDIYLFPHPKGYQITFRQNNQQRLYRQIDQSLGEKVLVHLKYLADMDVAEKRRMQVGSATYPLDEKVALRLRFSTVA…
I9XES1 2-215 SSNLANGERVQIVLSPVTVNDETISISIRIPSKTTYPHSFFEEQGFYNLLDNKEQAISAIKDGIAIGKNVIVCGGTGSGKTTYIKSI…
A0A1C2JMI4 259-460 None
A0A833IZU9 297-540 None
A0A7Y5AZ47 102-419 None
A0A348XDW8 300-601 None
A0A812YN14 8-305 None
A0A2N0EX20 11-246 None
A0A1T1D669 263-559 None
A0A7W0SKA4 10-325 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.