DPCstruct | MC18933

Metacluster Properties and Pfam Annotations

Number of structural domains61
Mean domain length (aa)131 ± 26 aa
Standard deviation of domain lengths26.19
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.39
Mean fraction of residues predicted as intrinsically disordered0.68
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)38.09
Pfam Score98.86
Assigned Pfam label(s) CL0123- CL0260

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S2MQ05 325-445 ETPRRARESWMYEKAANIRKLGGERWDPKKKLSPEALEGIRALHAQDSERFSTPNLARHFEVSPEAIKRILKSKWKPTAEEAVKRDL…
A0A3M2T9S2 1-131 MEKPHPQSKASKEHSGEKSDETKTEEKKQEGWQLQKEALKNKFKEGWNPLRKVSPDAIEGIRQLHAAAPQQFKTPVLAEQFKLSPDA…
A0A3N4KR87 228-399 None
A0A162MUC3 80-234 None
A0A0F7SAU6 257-403 None
A0A099NZM5 23-169 None
A0A4Q2DH20 77-221 None
W2S3C6 65-219 None
A0A1Z5SM85 62-191 None
A0A7J7S5B0 3-75 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.