DPCstruct | MC18925

Metacluster Properties and Pfam Annotations

Number of structural domains254
Mean domain length (aa)183 ± 28 aa
Standard deviation of domain lengths27.97
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.99
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)13.51
Pfam Score100.00
Assigned Pfam label(s) PF20062

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S2YHU2 6-198 KTSWLAVQDATPEDVCDALGLRQRQYMDWTSGTHAAYRSGVFVIRPVPAWTIAHGRIHLPPEIDLTDPRFPAWLESMSTRLGDLQFF…
A0A348S2B0 78-268 KYVFGQPERWMAFRTRNIGTVRNALGLTNTEVCSWVQGLSKATERHLFITPPIRGWVLVFGHYLPNPSEDIDTFYKYMRNLSKEVGE…
L7KJW5 10-215 None
G8S356 10-167 None
A0A1P8WQK4 14-228 None
A0A838RP33 17-208 None
A0A1T3NLD9 29-196 None
A0A810LHV4 3-200 None
A0A7K0BTA3 1-156 None
A0A2P9IJ62 3-136 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.