DPCstruct | MC18924

Metacluster Properties and Pfam Annotations

Number of structural domains216
Mean domain length (aa)108 ± 19 aa
Standard deviation of domain lengths19.17
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score80.04
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)21.40
Pfam Score79.34
Assigned Pfam label(s) CL0233- CL0299- PF05610- PF01521

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7U6KQS0 2-81 IEMTERAAQHVQDFLDNRGKGEGIRVGIRTAGCSGLAYVLEFVDIPDENDTRYESRGVSIFIDPKSLVYLDGLLMDYEKK
A0A2E9EZT4 4-108 CTLTDAAKQQIDTICKENEVYAVTLNMKGGGCAGFEYKWGTYKTADELLDDDEVFTTDNKNVFVIGGASIMFLFGTVIDYKKDIMGS…
A0A7R8X5Z7 3-84 None
A0A6V7SGS7 181-300 None
A0A1M6STG8 48-161 None
A0A158N7W1 93-198 None
A0A0N1MCF8 6-91 None
A0A0M3IHL7 387-494 None
A0A6V7WMJ7 29-137 None
A0A6V7WPC2 24-132 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.