DPCstruct | MC18916

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)92 ± 12 aa
Standard deviation of domain lengths12.16
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.34
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)59.15
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A443S4I1 2-92 AFRSFGHLLRYGDAPIKRAVPLALALISISNPKLNILETLSKFSHDSDTEVACNAIFAMGLIGAGTNNARLSTMLRQLAQFHNKEAN…
A0A6I9P5R0 23-132 IAMGEEIGSEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPEVSHNSIFAMGMVGSGESPHTHPIETC…
A0A7J6YL94 1027-1128 None
A0A7R9DCF2 71-144 None
A0A0A9XYD3 4-79 None
G3I308 2-75 None
A0A7J8LQ48 253-355 None
A0A267E222 423-524 None
A0A2C6L2A5 42-138 None
A0A813K8H6 523-624 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.