DPCstruct | MC18912

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)168 ± 29 aa
Standard deviation of domain lengths29.19
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score81.78
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)27.01
Pfam Score98.04
Assigned Pfam label(s) PF05340- PF05266- CL0268

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A835LYG2 1-168 MMHSSPSQHIEAILPLPCRSLPFRKSSLMWGSIEFMEVFKVLPQQPHLCPLEQYNEEAREGIAIGKMLIFANLVKETMELQLDVPRS…
A0A6J0KXG4 3-152 LPFEKKLPIWKRVESMEVYKRFPQSPHFIPLLESREDCREMSAVGMMLTFSGLLEEVKTLQLNSPISSLNSLSDSFAELEKHGFDVQ…
A0A6P6GHZ4 1-158 None
A0A2G5DR35 346-548 None
A0A6D2HF37 1-131 None
A0A164YXB3 2-163 None
A0A0K9QNR6 131-314 None
A0A803Q3L3 340-545 None
A0A565CJ37 5-110 None
A0A2G5DDW1 6-156 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.