DPCstruct | MC18909

Metacluster Properties and Pfam Annotations

Number of structural domains33
Mean domain length (aa)178 ± 36 aa
Standard deviation of domain lengths36.32
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score67.75
Mean fraction of residues predicted as intrinsically disordered0.55
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)33.05
Pfam Score100.00
Assigned Pfam label(s) PF08597

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y2GXU0 1-154 MPKPNLVPENETEEEKFERRQREKNAIIESDIANAADLFSGVKVTDEVVTSASKLETMKPKTKEQFAEFTTELVALIQKHEKQGLYV…
A0A835LT79 20-173 KYAYNDEDVEDNEEKSTLVGAPAPKQNTRKSVEKKGTNENPLAEKLRQQRLVEEADYKLTTELFGNTDDEKSLDNFIPKSESDFSEY…
A0A183WYY1 5-175 None
A0A251RPB5 23-173 None
A0A3B3VJZ3 7-239 None
A0A1Y1WD79 37-237 None
L8Y420 48-291 None
T1FWB9 23-178 None
A0A1B0B6F1 21-195 None
A0A078HN04 80-295 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.