DPCstruct | MC18895

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)71 ± 7 aa
Standard deviation of domain lengths7.39
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score78.11
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)41.52
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0F5IIU0 12-76 VVAKANCTLVAYSTKSVAVFGDTQPIINQLKEMGGSFNSRLTLNGKKVEGWIFPKSKEPRLAYYF
A0A6C0H482 1-68 MSGIYIEEYSPKSFVVRGNTKDYKDSLLALGGKWNSSLTDKKSGDKFGAWLFWGDKQNQISEWIEKGC
A0A6C0JQG2 1-60 None
A0A2V3PYH8 221-294 None
R7JK54 105-184 None
A0A3E4Z6Y5 305-374 None
A0A7X6URS8 110-175 None
D1K5B5 161-229 None
A0A7Z6S1R0 100-173 None
A0A060R8M2 490-552 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.