DPCstruct | MC18861

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)585 ± 106 aa
Standard deviation of domain lengths105.98
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score63.82
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.34
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)17.53
Pfam Score80.69
Assigned Pfam label(s) PF14613- PF19343

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A139AXS6 263-730 VERDLPATFTQEERGSRPERKTSSYVDDAADVIAERLSVEKRQRLVDRFRRICEDLSGNEGYRSSIKYLLSMLERLASATVGGGQDV…
A0A7S1A4I1 479-911 DRKVKQKALELCSATQTYLSGRFGIEDTAGMDSWLQTLRGHVLEHLGLQRAMLVDSLSGLRLDHLDLRHFISSSWDPVSVESQLQVA…
E4ZYR4 37-593 None
A0A0F4Z307 30-774 None
A0A146HPE3 90-762 None
A0A094IV52 29-793 None
A0A4Z0AAK2 7-697 None
F4RIZ2 47-579 None
A0A381LF51 30-624 None
A0A060SNU9 24-528 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.