DPCstruct | MC18852

Metacluster Properties and Pfam Annotations

Number of structural domains5
Mean domain length (aa)56 ± 4 aa
Standard deviation of domain lengths3.87
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score93.86
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.97
Mean intra-cluster local Distance Difference Test score0.96
Mean intra-cluster sequence similarity (%)88.52
Pfam Score100.00
Assigned Pfam label(s) PF00421

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A452XD64 1-59 LSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPVFRDKEGRELFV
A0A7J7L242 260-313 SESWSKIPEKLVFYDYIGNNPAKGGLFRAGLMDNGDGIAVRWLGHPAFRDRGGA
J3MZ32 91-148 None
A0A1R3KJE0 193-251 None
A0A1Z5R6G3 114-162 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.