DPCstruct | MC18841

Metacluster Properties and Pfam Annotations

Number of structural domains55
Mean domain length (aa)256 ± 46 aa
Standard deviation of domain lengths45.95
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score88.69
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)19.98
Pfam Score100.00
Assigned Pfam label(s) CL0477

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A380EL23 25-271 QRDINYENYLPMYDSKDIENSIYLDQFNGVNSARDNWVTNFSNEKALVNAKLLVDNYNSEIDRLIDILDSRERINLVNKDETFISWT…
A0A6B1NWD5 258-473 PFTPAPQSGWDTFPALTELMPWCKPGVKPNRNWVISPSKTILHRRWNRLVQEPDPATKQELFKETRDRTLDKDALQIPGHPHPPTCL…
A0A847F800 16-292 None
A0A838L135 228-518 None
A0A5C8DIN1 157-440 None
S3JEV1 23-296 None
A0A4U8TPN2 887-1267 None
A0A6P0RFX3 8-257 None
A0A650EMJ9 6-305 None
A0A0M1J4B9 72-381 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.