DPCstruct | MC18821

Metacluster Properties and Pfam Annotations

Number of structural domains102
Mean domain length (aa)517 ± 121 aa
Standard deviation of domain lengths120.71
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score78.56
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)19.83
Pfam Score97.93
Assigned Pfam label(s) CL0016- PF03169- PF07058

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X7G125 413-906 HWARPLLNWMVLIVLTYIILMTFNILIFRQWAYNEKLIYPLAQLPELLTDSGDDKHWIPEVYRTGFFWCGFLVSGGILGWNLLCKSG…
A0A1D6L4S1 13-561 CALLIVLTTQILGYGWAGLLRRYLVDPAEMWWPSNLAQVSLFRALHEKEEEGGKSRGPSRMRFFLIVFFASFAYYALPGYLLPILTF…
K9GCJ5 24-346 None
A0A446NAY1 20-510 None
A0A4S4CWP1 250-734 None
A0A4S4DPC3 40-494 None
A0A287XHG5 17-437 None
A0A6A6LGB8 19-474 None
A0A284RBK7 57-709 None
A0A0D2NBS0 401-1105 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.