DPCstruct | MC18792

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)338 ± 44 aa
Standard deviation of domain lengths44.48
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score81.01
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)18.69
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W0FXF1 6-281 TDPKLKALLDNFGVSEAGRKAIGYIQEILRVSYKNGFDDKFYNCLNKLGADFVIEKIIKPTVSLLRARGKALEVIEGTTDEGVKTRL…
I0FEB0 17-343 CKTQTSPQTTSTDTKKHLMSTLTEFDETPTEIRTTISQTQQPDDIIDIDTIKSQDIEEALNFIKEALNQATSQDRKIDAEAKINELT…
W5SKZ9 6-406 None
W5SPZ8 44-425 None
T1ECR8 7-347 None
W5SKH7 29-389 None
W5T220 449-740 None
W5T2B1 16-309 None
W5SBK1 120-455 None
W5SK75 9-358 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.