DPCstruct | MC18764

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)136 ± 19 aa
Standard deviation of domain lengths18.72
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score71.14
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)19.27
Pfam Score92.86
Assigned Pfam label(s) PF04246- PF17188

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5K7YJ81 1-101 MKVEAINTADARVGDRIVLNIQTSSLLKATFLLYVFPILAMIAGAVLGQTVAGMRSMDPSGLSALFGFLFFGLAFIVIRITGRRLSK…
A0A7C4X771 2-141 LKELGMVEDVMNKEVVVRLSKGEHCQTCPSKGMCHLGHDEERLVKVKTDIKLVKGQVVEIGIPEGELLKLSFLVYFLPILSLMVFST…
A0A2Z2NZX8 1-143 None
A0A4R5H949 2-150 None
A0A2G2LBG4 16-171 None
A0A355IU26 1-134 None
A0A2N6FMC2 4-144 None
A0A2E2HEW2 84-232 None
A0A368NPM5 3-159 None
A0A257LSD9 66-189 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.