DPCstruct | MC18756

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)172 ± 20 aa
Standard deviation of domain lengths20.27
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score92.58
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)29.85
Pfam Score100.00
Assigned Pfam label(s) CL0727

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3N9PCG2 300-461 IWKVQNTRSAAELEAFLSKLRIHQIAHQDDTIDWMLENFPDLFIIYSKKTYQGMFGGSDPISNLEWVNMNIRANHGSLGAAYPPAGM…
A0A2E0SJ19 6-151 DQDRIAGWMGEQFPGMFYIVSRSGTAAFRGMYLTGDEALTSKKWVTEHVSSKGPLGALYPLRTATHSNIHNCLKEGDTPSWFFFLPA…
A0A7V2V393 494-646 None
A0A7L6B492 351-493 None
A0A7W4GS63 140-320 None
A0A5C5ZA69 433-621 None
A0A7X8MA94 3-140 None
A0A1I2KTV6 7-130 None
B5JCV4 527-714 None
A0A5B9W2G0 697-869 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.