DPCstruct | MC18719

Metacluster Properties and Pfam Annotations

Number of structural domains64
Mean domain length (aa)138 ± 20 aa
Standard deviation of domain lengths19.73
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score86.17
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.56
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A428K4K1 92-217 ISFKDFPADVFKGQLADPDFSTNPDVKSFITRIKNECANGINFAGHYTLVTWGCGSTCQSGVLVDRKTGKIFSGVDTSLGSKFKKDS…
A0A435K2N4 2-120 YLKGKSALPKFAGSAAQFKTRIRNGMKSGPNYGGHFTMIEIGCGTSCIFAFLIDGRDGRVVDFPLGGEDNYQLQLRYGIDSTLLQAD…
A0A2N2WD84 97-242 None
A0A6L3ZF33 238-361 None
F8J639 13-162 None
A0A2D6IL56 141-284 None
A0A1J0ET16 4-141 None
A0A3S0QTW6 200-332 None
A0A1F6FIN3 20-159 None
A0A519T272 4-99 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.