DPCstruct | MC18709

Metacluster Properties and Pfam Annotations

Number of structural domains12069
Mean domain length (aa)154 ± 28 aa
Standard deviation of domain lengths27.61
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.12
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.34
Mean intra-cluster sequence similarity (%)10.50
Pfam Score33.95
Assigned Pfam label(s) CL0103- CL0219- CL0001- PF01973- CL0045

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1H5PHD9 105-244 None
A0A1I3HS60 210-350 None
A0A7W4AY20 37-192 None
A0A1Q8UU86 905-1011 None
W1PXM4 28-165 None
A0A4U7AZT5 1143-1273 None
A0A4U7BBG5 892-1071 None
A0A4V6YAX7 165-309 None
E8R302 294-412 None
A0A3S8X033 417-540 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.