DPCstruct | MC18709

Metacluster Properties and Pfam Annotations

Number of structural domains12069
Mean domain length (aa)154 ± 28 aa
Standard deviation of domain lengths27.61
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.12
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.34
Mean intra-cluster sequence similarity (%)10.50
Pfam Score33.95
Assigned Pfam label(s) CL0103- CL0219- CL0001- PF01973- CL0045

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812AKW1 40-218 None
F8Q0E2 2-105 None
A0A4R6K6K0 36-181 None
A0A7K3MLR2 3-111 None
A0A4X3PBG3 414-643 None
H3DWG9 421-631 None
A0A448ZFE0 386-544 None
A0A1F8RJ76 37-219 None
A0A1F8RE89 54-189 None
A0A3A5MPY8 318-436 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.